1tmk: Difference between revisions

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|PDB= 1tmk |SIZE=350|CAPTION= <scene name='initialview01'>1tmk</scene>, resolution 2.1&Aring;
|PDB= 1tmk |SIZE=350|CAPTION= <scene name='initialview01'>1tmk</scene>, resolution 2.1&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=TMP:THYMIDINE-5&#39;-PHOSPHATE'>TMP</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TMP:THYMIDINE-5&#39;-PHOSPHATE'>TMP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span>
|GENE= CDC8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
|GENE= CDC8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tmk OCA], [http://www.ebi.ac.uk/pdbsum/1tmk PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tmk RCSB]</span>
}}
}}


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[[Category: Lavie, A.]]
[[Category: Lavie, A.]]
[[Category: Schlichting, I.]]
[[Category: Schlichting, I.]]
[[Category: SO4]]
[[Category: TMP]]
[[Category: enzyme]]
[[Category: enzyme]]
[[Category: kinase]]
[[Category: kinase]]
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[[Category: transferase (phosphotransferase)]]
[[Category: transferase (phosphotransferase)]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:58:13 2008''

Revision as of 20:58, 30 March 2008

File:1tmk.jpg


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1tmk, resolution 2.1Å
Ligands: SO4, TMP
Gene: CDC8 (Saccharomyces cerevisiae)
Activity: dTMP kinase, with EC number 2.7.4.9
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



YEAST THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE MONOPHOSPHATE (DTMP)


About this Structure

1TMK is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation., Lavie A, Vetter IR, Konrad M, Goody RS, Reinstein J, Schlichting I, Nat Struct Biol. 1997 Aug;4(8):601-4. PMID:9253404

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