2pxi: Difference between revisions

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|PDB= 2pxi |SIZE=350|CAPTION= <scene name='initialview01'>2pxi</scene>, resolution 2.10&Aring;
|PDB= 2pxi |SIZE=350|CAPTION= <scene name='initialview01'>2pxi</scene>, resolution 2.10&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=GFH:'>GFH</scene>
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DOC:2&#39;,3&#39;-DIDEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=GFH:2&#39;-DEOXY-5&#39;-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE'>GFH</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= POLB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2iso|2ISO]], [[2isp|2ISP]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pxi OCA], [http://www.ebi.ac.uk/pdbsum/2pxi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pxi RCSB]</span>
}}
}}


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[[Category: Pedersen, L C.]]
[[Category: Pedersen, L C.]]
[[Category: Wilson, S H.]]
[[Category: Wilson, S H.]]
[[Category: CL]]
[[Category: GFH]]
[[Category: MG]]
[[Category: NA]]
[[Category: chiral interaction]]
[[Category: chiral interaction]]
[[Category: dna polymerase]]
[[Category: dna polymerase]]
Line 35: Line 34:
[[Category: transferase/dna complex]]
[[Category: transferase/dna complex]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:42:03 2008''

Revision as of 01:42, 31 March 2008

File:2pxi.jpg


Drag the structure with the mouse to rotate
2pxi, resolution 2.10Å
Ligands: CL, DA, DC, DG, DOC, DT, GFH, MG, NA
Gene: POLB (Homo sapiens)
Related: 2ISO, 2ISP


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate


About this Structure

2PXI is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta., McKenna CE, Kashemirov BA, Upton TG, Batra VK, Goodman MF, Pedersen LC, Beard WA, Wilson SH, J Am Chem Soc. 2007 Dec 19;129(50):15412-3. Epub 2007 Nov 22. PMID:18031037

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