2pzf: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 4: Line 4:
|PDB= 2pzf |SIZE=350|CAPTION= <scene name='initialview01'>2pzf</scene>, resolution 2.000&Aring;
|PDB= 2pzf |SIZE=350|CAPTION= <scene name='initialview01'>2pzf</scene>, resolution 2.000&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>
|LIGAND= <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[1xmi|1XMI]], [[1xmj|1XMJ]], [[2bb0|2BB0]], [[2bbs|2BBS]], [[2bbt|2BBT]], [[1r0z|1R0Z]], [[1r10|1R10]], [[2ixe|2IXE]], [[1l2t|1L2T]], [[1q12|1Q12]], [[1xef|1XEF]], [[2hyd|2HYD]], [[2pze|2PZE]], [[2pzg|2PZG]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzf OCA], [http://www.ebi.ac.uk/pdbsum/2pzf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pzf RCSB]</span>
}}
}}


'''Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508'''
'''Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508'''


==Disease==
Known diseases associated with this structure: Congenital bilateral absence of vas deferens OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Cystic fibrosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Hypertrypsinemia, neonatal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Pancreatitis, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Sweat chloride elevation without CF OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]]


==About this Structure==
==About this Structure==
Line 34: Line 34:
[[Category: Wasserman, S R.]]
[[Category: Wasserman, S R.]]
[[Category: Zhao, X.]]
[[Category: Zhao, X.]]
[[Category: ATP]]
[[Category: MG]]
[[Category: abc transporter]]
[[Category: abc transporter]]
[[Category: cftr]]
[[Category: cftr]]
Line 42: Line 40:
[[Category: nbd]]
[[Category: nbd]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:41:52 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:42:44 2008''