Collagen: Difference between revisions
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This illustration depicts a basement membrane, which forms a tough surface that supports the skin and many organs. A different collagen--"type IV"--forms the structural basis of this membrane. Type IV collagen has a globular head at one end and an extra tail at the other. The heads bind strongly together, head-to-head, and four collagen molecules associate together through their tails, forming an X-shaped complex. Using these two types of interactions, type IV collagen forms an extended network, shown above in light blue. Two other molecules--cross-shaped laminin (blue- green) and long, snaky proteoglycans (green)--fill in the spaces, forming a dense sheet. | This illustration depicts a basement membrane, which forms a tough surface that supports the skin and many organs. A different collagen--"type IV"--forms the structural basis of this membrane. Type IV collagen has a globular head at one end and an extra tail at the other. The heads bind strongly together, head-to-head, and four collagen molecules associate together through their tails, forming an X-shaped complex. Using these two types of interactions, type IV collagen forms an extended network, shown above in light blue. Two other molecules--cross-shaped laminin (blue- green) and long, snaky proteoglycans (green)--fill in the spaces, forming a dense sheet. | ||
[[Image:MotM Painting.gif|left]] | [[Image:MotM Painting.gif|left |300px]] | ||
