2jit: Difference between revisions

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==~~CRYSTAL STRUCTURE OF~~ EGFR ~~KINASE DOMAIN~~ T790M ~~MUTATION~~==

==Crystal structure of EGFR kinase domain T790M mutation==

== Structural highlights ==

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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jit OCA], [http://pdbe.org/2jit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jit RCSB], [http://www.ebi.ac.uk/pdbsum/2jit PDBsum]</span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jit OCA], [http://pdbe.org/2jit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jit RCSB], [http://www.ebi.ac.uk/pdbsum/2jit PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jit ProSAT]</span></td></tr>

</table>

== Disease ==

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Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jit_consurf.spt"</scriptWhenChecked>

<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jit_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jit ConSurf].

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@@ Line 1: / Line 1: @@
-==CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION==
+==Crystal structure of EGFR kinase domain T790M mutation==
 <StructureSection load='2jit' size='340' side='right' caption='[[2jit]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
 == Structural highlights ==
@@ Line 5: / Line 6: @@
 </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dnq|1dnq]], [[1dnr|1dnr]], [[1ivo|1ivo]], [[1m14|1m14]], [[1m17|1m17]], [[1mox|1mox]], [[1nql|1nql]], [[1xkk|1xkk]], [[1yy9|1yy9]], [[1z9i|1z9i]], [[2gs2|2gs2]], [[2gs7|2gs7]], [[2itn|2itn]], [[2ito|2ito]], [[2itp|2itp]], [[2itq|2itq]], [[2itt|2itt]], [[2itu|2itu]], [[2itv|2itv]], [[2itw|2itw]], [[2itx|2itx]], [[2ity|2ity]], [[2itz|2itz]], [[2j5e|2j5e]], [[2j5f|2j5f]], [[2j6m|2j6m]], [[2jiu|2jiu]], [[2jiv|2jiv]]</td></tr>
 <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jit OCA], [http://pdbe.org/2jit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jit RCSB], [http://www.ebi.ac.uk/pdbsum/2jit PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jit OCA], [http://pdbe.org/2jit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jit RCSB], [http://www.ebi.ac.uk/pdbsum/2jit PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jit ProSAT]</span></td></tr>
 </table>
 == Disease ==
@@ Line 15: / Line 16: @@
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jit_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jit_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jit ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">