1w3c: Difference between revisions

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==CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS3 PROTEASE IN COMPLEX WITH A PEPTIDOMIMETIC INHIBITOR==
==Crystal structure of the Hepatitis C Virus NS3 Protease in complex with a peptidomimetic inhibitor==
<StructureSection load='1w3c' size='340' side='right' caption='[[1w3c]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1w3c' size='340' side='right' caption='[[1w3c]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1w3c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_(isolate_1) Hepatitis c virus (isolate 1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W3C FirstGlance]. <br>
<table><tr><td colspan='2'>[[1w3c]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W3C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DN1:3-({(2S)-2-[({(1R)-1-[({(1R)-1-[(R)-CARBOXY(HYDROXY)METHYL]-3,3-DIFLUOROPROPYL}AMINO)CARBONYL]-3-METHYLBUTYL}AMINO)CARBONYL]-2,3-DIHYDRO-1H-INDOL-2-YL}METHYL)THIOPHENE-2-CARBOXYLIC+ACID'>DN1</scene>, <scene name='pdbligand=DN2:3-({(2S)-2-[({(1S)-1-[({(1S)-1-[(R)-CARBOXY(HYDROXY)METHYL]-3,3-DIFLUOROPROPYL}AMINO)CARBONYL]-3-METHYLBUTYL}AMINO)CARBONYL]-2,3-DIHYDRO-1H-INDOL-2-YL}METHYL)THIOPHENE-2-CARBOXYLIC+ACID'>DN2</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DN1:3-({(2S)-2-[({(1R)-1-[({(1R)-1-[(R)-CARBOXY(HYDROXY)METHYL]-3,3-DIFLUOROPROPYL}AMINO)CARBONYL]-3-METHYLBUTYL}AMINO)CARBONYL]-2,3-DIHYDRO-1H-INDOL-2-YL}METHYL)THIOPHENE-2-CARBOXYLIC+ACID'>DN1</scene>, <scene name='pdbligand=DN2:3-({(2S)-2-[({(1S)-1-[({(1S)-1-[(R)-CARBOXY(HYDROXY)METHYL]-3,3-DIFLUOROPROPYL}AMINO)CARBONYL]-3-METHYLBUTYL}AMINO)CARBONYL]-2,3-DIHYDRO-1H-INDOL-2-YL}METHYL)THIOPHENE-2-CARBOXYLIC+ACID'>DN2</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dxp|1dxp]], [[1dy8|1dy8]], [[1dy9|1dy9]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w3c OCA], [http://pdbe.org/1w3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w3c RCSB], [http://www.ebi.ac.uk/pdbsum/1w3c PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w3c OCA], [http://pdbe.org/1w3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w3c RCSB], [http://www.ebi.ac.uk/pdbsum/1w3c PDBsum]</span></td></tr>
</table>
</table>
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[[Category: Hcv]]
[[Category: Hcv]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Indoline-based peptidomimetic inhibito]]
[[Category: Indoline-based peptidomimetic inhibitor]]
[[Category: Serine protease]]
[[Category: Serine protease]]
Retrieved from "https://proteopedia.org/1w3c"