2hek: Difference between revisions
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|GENE= | |GENE= | ||
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00077 HDc], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1078 COG1078]</span> | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00077 HDc], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1078 COG1078]</span> | ||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hek OCA], [http://www.ebi.ac.uk/pdbsum/2hek PDBsum | |RELATEDENTRY= | ||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hek OCA], [http://www.ebi.ac.uk/pdbsum/2hek PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hek RCSB]</span> | |||
}} | }} | ||
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[[Category: unknown function]] | [[Category: unknown function]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:29:15 2008'' | ||
Revision as of 00:29, 31 March 2008
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| 2hek, resolution 1.997Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sites: | AC1, AC2, AC3, AC4, AC5, AC6, AC7, AC8, AC9, BC1, BC2, BC3, BC4, BC5, BC6, BC7, BC8, BC9, CC1, CC2, CC3 and CC4 | ||||||||||||
| Ligands: | BR, CL, GDP, GOL, PO4, ZN | ||||||||||||
| Domains: | HDc, COG1078 | ||||||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution.
Overview
Using single-wavelength anomalous dispersion data obtained from a gold-derivatized crystal, the X-ray crystal structure of the protein 067745_AQUAE from the prokaryotic organism Aquifex aeolicus has been determined to a resolution of 2.0 A. Amino-acid residues 1-371 of the 44 kDa protein were identified by Pfam as an HD domain and a member of the metal-dependent phosphohydrolase superfamily (accession No. PF01966). Although three families from this large and diverse group of enzymatic proteins are represented in the PDB, the structure of 067745_AQUAE reveals a unique fold that is unlike the others and that is likely to represent a new subfamily, further organizing the families and characterizing the proteins. Data are presented that provide the first insights into the structural organization of the proteins within this clan and a distal alternative GDP-binding domain outside the metal-binding active site is proposed.
About this Structure
2HEK is a Single protein structure of sequence from Aquifex aeolicus. Full crystallographic information is available from OCA.
Reference
Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus., Oganesyan V, Adams PD, Jancarik J, Kim R, Kim SH, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 May 1;63(Pt, 5):369-74. Epub 2007 Apr 28. PMID:17565173
Page seeded by OCA on Mon Mar 31 03:29:15 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Aquifex aeolicus
- Single protein
- Adams, P D.
- BSGC, Berkeley Structural Genomics Center.
- Jancarik, J.
- Kim, R.
- Kim, S H.
- Oganesyan, V.
- Berkeley structural genomics center
- Bsgc
- Predominantly alpha helical protein with gdp binding site and active site being far from each other
- Protein structure initiative
- Psi
- Structural genomic
- Unknown function
