5du7: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5du7 is ~~ON HOLD until Paper Publication~~

==Crystal structure of ldtMt2 at 1.79 Angstrom resolution==

~~Authors~~: ~~Kumar~~, P., ~~Lamichhane~~, G.

== Structural highlights ==

<table><tr><td colspan='2'>[[5du7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DU7 FirstGlance]. <br>

~~Description: Crystal structure of ldtMt2 at 1.79 Angstrom resolution~~

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5duj|5duj]]</td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5du7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5du7 OCA], [http://pdbe.org/5du7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5du7 RCSB], [http://www.ebi.ac.uk/pdbsum/5du7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5du7 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/LDT2_MYCTO LDT2_MYCTO]] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection.<ref>PMID:20305661</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Kumar, P]]

[[Category: Lamichhane, G]]

[[Category: Cell wall enzyme]]

[[Category: Peptidoglycan synthesis enzyme]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5du7 is ON HOLD  until Paper Publication
+==Crystal structure of ldtMt2 at 1.79 Angstrom resolution==
+<StructureSection load='5du7' size='340' side='right' caption='[[5du7]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
-Authors: Kumar, P., Lamichhane, G.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5du7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DU7 FirstGlance]. <br>
-Description: Crystal structure of ldtMt2 at 1.79 Angstrom resolution
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5duj|5duj]]</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5du7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5du7 OCA], [http://pdbe.org/5du7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5du7 RCSB], [http://www.ebi.ac.uk/pdbsum/5du7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5du7 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/LDT2_MYCTO LDT2_MYCTO]] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection.<ref>PMID:20305661</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Kumar, P]]
 [[Category: Lamichhane, G]]
+[[Category: Cell wall enzyme]]
+[[Category: Peptidoglycan synthesis enzyme]]
+[[Category: Transferase]]