4uvi: Difference between revisions
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==Discovery of pyrimidine isoxazoles InhA in complex with compound 23== | ==Discovery of pyrimidine isoxazoles InhA in complex with compound 23== | ||
<StructureSection load='4uvi' size='340' side='right' caption='[[4uvi]], [[Resolution|resolution]] 1.73Å' scene=''> | <StructureSection load='4uvi' size='340' side='right'caption='[[4uvi]], [[Resolution|resolution]] 1.73Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4uvi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UVI FirstGlance]. <br> | <table><tr><td colspan='2'>[[4uvi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UVI FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KXU:5-{[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]METHYL}-N-[(2-METHYLPYRIDIN-4-YL)METHYL]-1,2-OXAZOLE-3-CARBOXAMIDE'>KXU</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KXU:5-{[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]METHYL}-N-[(2-METHYLPYRIDIN-4-YL)METHYL]-1,2-OXAZOLE-3-CARBOXAMIDE'>KXU</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uvd|4uvd]], [[4uve|4uve]], [[4uvg|4uvg]], [[4uvh|4uvh]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uvd|4uvd]], [[4uve|4uve]], [[4uvg|4uvg]], [[4uvh|4uvh]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvi OCA], [http://pdbe.org/4uvi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uvi RCSB], [http://www.ebi.ac.uk/pdbsum/4uvi PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvi OCA], [http://pdbe.org/4uvi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uvi RCSB], [http://www.ebi.ac.uk/pdbsum/4uvi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
==See Also== | |||
*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Myctu]] | |||
[[Category: Cowan, S]] | [[Category: Cowan, S]] | ||
[[Category: Ghorpade, S]] | [[Category: Ghorpade, S]] | ||
Revision as of 08:29, 23 May 2019
Discovery of pyrimidine isoxazoles InhA in complex with compound 23
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