Stepler sandbox STAT3: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==STAT3== | ==STAT3== | ||
<StructureSection load='1bg1' size='340' side='right' caption='STAT3 Interacting with DNA' scene=''> | <StructureSection load='1bg1' size='340' side='right' caption='STAT3 Interacting with DNA' scene=''> | ||
STAT3 (Signal Transducer and Activator of Transcription 3) is one of seven of a family of homologous STAT proteins that differentially regulate gene expression. STAT 3 is important in both the development of embryos and | |||
many functions in adult organisms. The STAT3 protein is composed of several helix-turn-helix structures and its quaternary structure consists of two STAT3 proteins dimerized with themselves. <ref>PMID:9671298</ref> | |||
== Structure == | == Structure == | ||
<scene name='71/714950/Stat3_dimer_and_dna/1'> | The STAT3 protein is composed of several helix-turn-helix structures and its quaternary structure consists of two STAT3 proteins dimerized with themselves. <ref>PMID:9671298</ref> | ||
The <scene name='71/714950/Stat3_dimer_and_dna/1'>STAT3 protein interacts with DNA</scene> by binding to the major groove of the DNA. | |||
== Regulation == | == Regulation == | ||
== DNA-Protein Interactions == | == DNA-Protein Interactions == | ||
The <scene name='71/714950/Stat3_dimer_and_dna/1'>STAT3 protein interacts with DNA</scene> by binding to the major groove of the DNA. | |||
== Structural highlights == | == Structural highlights == | ||
