Barnase: Difference between revisions
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== Function == | == Function == | ||
'''Barnase''' (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA. | '''Barnase''' (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA. | ||
== Relevance == | == Relevance == | ||
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== Structural highlights == | == Structural highlights == | ||
BA hydrolyzes RNA at GpN sites where the active site positively charged Lys and Arg coordinate the RNA phosphate group. | BA hydrolyzes RNA at GpN sites where the <scene name='44/442736/Cv/3'>active site positively charged Lys and Arg coordinate the RNA phosphate group</scene>.<ref>PMID:8110767</ref> | ||
</StructureSection> | </StructureSection> | ||
