Caffeine: Difference between revisions
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Adenosine is an inhibitory neurotransmitter, which promotes sleep and inhibits arousal. It has two components; an adenine nucleotide and a ribose sugar. Adenosine is a polar molecule and is water soluble. Within the brain, concentration of this neuromodulator increases every hour. Adenosine binds extracellularly to G-protein and induces multiple effects. The G-protein is composed of 7 alpha helices, which provide its secondary structure, and is a transmembrane protein. As adenosine receptors bind G-protein, neural activity begins to decrease and the person feels fatigued and sleepy. A2A receptor is one of many adenosine G protein-coupled receptors. | Adenosine is an inhibitory neurotransmitter, which promotes sleep and inhibits arousal. It has two components; an adenine nucleotide and a ribose sugar. Adenosine is a polar molecule and is water soluble. Within the brain, concentration of this neuromodulator increases every hour. Adenosine binds extracellularly to G-protein and induces multiple effects. The G-protein is composed of 7 alpha helices, which provide its secondary structure, and is a transmembrane protein. As adenosine receptors bind G-protein, neural activity begins to decrease and the person feels fatigued and sleepy. A2A receptor is one of many adenosine G protein-coupled receptors. | ||
<scene name='71/716555/Antagonist_binding/1'>A2A Receptor with Adenosine Bound</scene> | <scene name='71/716555/Antagonist_binding/1'>A2A Receptor with Adenosine Bound</scene> | ||
== Mechanism of Caffeine Synthesis == | == Mechanism of Caffeine Synthesis == | ||
