CCA-adding enzyme: Difference between revisions
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'''CCA-adding enzyme''' (CAE) builds or repairs the trinucleotice CCA at the 3’ end of tRNA. CAE has one active site which is capable of binding CTP and ATP in a specific sequence. In the bacteria Aquifex aeolicus, CAE consists of 2 subunits. One specific for CTP and the other for ATP. CAE builds the CCA without a genetic template. | '''CCA-adding enzyme''' (CAE) builds or repairs the trinucleotice CCA at the 3’ end of tRNA. CAE has one active site which is capable of binding CTP and ATP in a specific sequence. In the bacteria Aquifex aeolicus, CAE consists of 2 subunits. One specific for CTP and the other for ATP. CAE builds the CCA without a genetic template. | ||
<scene name='55/551188/Cv/2'>Structure of CCA-adding enzyme complex with tRNA 34-mer, CTP, ethanediol and Ca+2 ion</scene>. | *<scene name='55/551188/Cv/2'>Structure of CCA-adding enzyme complex with tRNA 34-mer, CTP, ethanediol and Ca+2 ion</scene> (PDB entry [[3ovs]]). | ||
*<scene name='55/551188/Cv/3'>Binding site of CCA-adding enzyme</scene> (PDB entry [[3ovs]]).<ref>PMID:21071662</ref> | |||
</StructureSection> | </StructureSection> | ||
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**[[3ovb]] – AfCAE + ATP + tRNA 35-mer<BR /> | **[[3ovb]] – AfCAE + ATP + tRNA 35-mer<BR /> | ||
}} | }} | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
