CD47: Difference between revisions
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== Function == | == Function == | ||
'''CD47 (Cluster of Differentiation 47)''' is a protein which is expressed by cancer cells to avoid detection by the immune system. CD47 is a receptor for thrombospondin-1 and their association influences cell migration and adhesion. CD47 is a receptor for SIRP1 and their association influences inhibition of phagocytosis. CD47 is a receptor for several integrins and their association influences cell migration and adhesion. CD47 leads to cell death via apoptosis. | '''CD47 (Cluster of Differentiation 47)''' is a protein which is expressed by cancer cells to avoid detection by the immune system. CD47 is a receptor for thrombospondin-1 and their association influences cell migration and adhesion. CD47 is a receptor for SIRP1 and their association influences inhibition of phagocytosis. CD47 is a receptor for several integrins and their association influences cell migration and adhesion. CD47 leads to cell death via apoptosis. <ref>PMID:22310103</ref> | ||
== Relevance == | == Relevance == | ||
