4xr5: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==X-ray structure of the unliganded thymidine phosphorylase from Salmonella typhimurium at 2.05 A resolution==

~~The entry~~ 4xr5 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4xr5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XR5 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XR5 FirstGlance].

~~Authors~~: ~~Balaev~~, V.V., ~~Lashkov, A~~.A., ~~Gabdulkhakov~~, A.G., ~~Betzel, C~~.~~, Mikhailov, A~~.M.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4x46|4x46]]</td></tr>

~~Description~~: ~~X-ray structure~~ of the ~~unliganded thymidine~~ phosphorylase ~~from Salmonella typhimurium at 2.05 A resolution~~

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] </td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xr5 OCA], [http://pdbe.org/4xr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xr5 RCSB], [http://www.ebi.ac.uk/pdbsum/4xr5 PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TYPH_SALTY TYPH_SALTY]] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

__TOC__

</StructureSection>

[[Category: Thymidine phosphorylase]]

[[Category: Balaev, V V]]

[[Category: Betzel, C]]

[[Category: Gabdulkhakov, A.G]]

[[Category: Gabdulkhakov, A G]]

[[Category: Mikhailov, A.M]]

[[Category: Lashkov, A A]]

[[Category: ~~Lashkov, A.A~~]]

[[Category: Mikhailov, A M]]

[[Category: ~~Balaev, V.V~~]]

[[Category: Metabolism]]

[[Category: Nucleoside]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==X-ray structure of the unliganded thymidine phosphorylase from Salmonella typhimurium at 2.05 A resolution==
+<StructureSection load='4xr5' size='340' side='right' caption='[[4xr5]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-The entry 4xr5 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xr5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XR5 FirstGlance]. <br>
-Authors: Balaev, V.V., Lashkov, A.A., Gabdulkhakov, A.G., Betzel, C., Mikhailov, A.M.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x46|4x46]]</td></tr>
-Description: X-ray structure of the unliganded thymidine phosphorylase from Salmonella typhimurium at 2.05 A resolution
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xr5 OCA], [http://pdbe.org/4xr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xr5 RCSB], [http://www.ebi.ac.uk/pdbsum/4xr5 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TYPH_SALTY TYPH_SALTY]] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
+__TOC__
+</StructureSection>
+[[Category: Thymidine phosphorylase]]
+[[Category: Balaev, V V]]
 [[Category: Betzel, C]]
-[[Category: Gabdulkhakov, A.G]]
+[[Category: Gabdulkhakov, A G]]
-[[Category: Mikhailov, A.M]]
+[[Category: Lashkov, A A]]
-[[Category: Lashkov, A.A]]
+[[Category: Mikhailov, A M]]
-[[Category: Balaev, V.V]]
+[[Category: Metabolism]]
+[[Category: Nucleoside]]
+[[Category: Transferase]]