4ym9: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 4ym9 is ~~ON HOLD until Paper Publication~~

==Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102==

~~Authors~~: ~~Hofbauer~~, S., ~~Brito~~, J.A., ~~Mulchande~~, J., ~~Nogly~~, P., ~~Pessanha~~, M.~~, Moreira, R~~., Archer, M.

== Structural highlights ==

<table><tr><td colspan='2'>[[4ym9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YM9 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YM9 FirstGlance].

~~Description~~: ~~Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=4E4:2-ETHYL-2-(HYDROXYMETHYL)-N-(6-METHYLPYRIDIN-3-YL)BUTANAMIDE'>4E4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ym9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ym9 OCA], [http://pdbe.org/4ym9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ym9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ym9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ym9 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG]] Acts upon elastin.

__TOC__

</StructureSection>

[[Category: Pancreatic elastase]]

[[Category: Sus scrofa]]

[[Category: Archer, M]]

[[Category: Brito, J A]]

[[Category: Hofbauer, S]]

[[Category: Moreira, R]]

[[Category: Mulchande, J]]

[[Category: Nogly, P]]

~~[[Category: Brito, J.A]]~~

~~[[Category: Mulchande, J]]~~

~~[[Category: Moreira, R]]~~

[[Category: Pessanha, M]]

[[Category: ~~Hofbauer, S~~]]

[[Category: Hydrolase]]

[[Category: ~~Archer, M~~]]

[[Category: Inhibitor]]

[[Category: Porcine pancreatic elastase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4ym9 is ON HOLD  until Paper Publication
+==Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102==
+<StructureSection load='4ym9' size='340' side='right' caption='[[4ym9]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors: Hofbauer, S., Brito, J.A., Mulchande, J., Nogly, P., Pessanha, M., Moreira, R., Archer, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4ym9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YM9 FirstGlance]. <br>
-Description: Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4E4:2-ETHYL-2-(HYDROXYMETHYL)-N-(6-METHYLPYRIDIN-3-YL)BUTANAMIDE'>4E4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ym9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ym9 OCA], [http://pdbe.org/4ym9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ym9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ym9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ym9 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG]] Acts upon elastin.
+__TOC__
+</StructureSection>
+[[Category: Pancreatic elastase]]
+[[Category: Sus scrofa]]
+[[Category: Archer, M]]
+[[Category: Brito, J A]]
+[[Category: Hofbauer, S]]
+[[Category: Moreira, R]]
+[[Category: Mulchande, J]]
 [[Category: Nogly, P]]
-[[Category: Brito, J.A]]
-[[Category: Mulchande, J]]
-[[Category: Moreira, R]]
 [[Category: Pessanha, M]]
-[[Category: Hofbauer, S]]
+[[Category: Hydrolase]]
-[[Category: Archer, M]]
+[[Category: Inhibitor]]
+[[Category: Porcine pancreatic elastase]]