4z4q: Difference between revisions

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'''Unreleased structure'''


The entry 4z4q is ON HOLD  until Paper Publication
==Quinazolinedione(PD 0305970)-DNA cleavage complex of topoisomerase IV from S. pneumoniae==
 
<StructureSection load='4z4q' size='340' side='right' caption='[[4z4q]], [[Resolution|resolution]] 3.04&Aring;' scene=''>
Authors: Laponogov, I., Veselkov, D.A., Pan, X.-S., Selvarajah, J., Crevel, I.M.-T., Fisher, L.M., Sanderson, M.R.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4z4q]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z4Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z4Q FirstGlance]. <br>
Description: Quinazolinedione(PD 0305970)-DNA cleavage complex of topoisomerase IV from S. pneumoniae
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PDQ:3-AMINO-7-{(3R)-3-[(1S)-1-AMINOETHYL]PYRROLIDIN-1-YL}-1-CYCLOPROPYL-6-FLUORO-8-METHYLQUINAZOLINE-2,4(1H,3H)-DIONE'>PDQ</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4koe|4koe]], [[4pxp|4pxp]], [[3rad|3rad]], [[3rae|3rae]], [[3raf|3raf]], [[3ksb|3ksb]], [[3ksa|3ksa]], [[4i3h|4i3h]]</td></tr>
[[Category: Fisher, L.M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z4q OCA], [http://pdbe.org/4z4q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z4q RCSB], [http://www.ebi.ac.uk/pdbsum/4z4q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z4q ProSAT]</span></td></tr>
[[Category: Pan, X.-S]]
</table>
[[Category: Sanderson, M.R]]
== Function ==
[[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Crevel, I M.T]]
[[Category: Fisher, L M]]
[[Category: Laponogov, I]]
[[Category: Pan, X S]]
[[Category: Sanderson, M R]]
[[Category: Selvarajah, J]]
[[Category: Selvarajah, J]]
[[Category: Veselkov, D.A]]
[[Category: Veselkov, D A]]
[[Category: Laponogov, I]]
[[Category: Cleavage complex]]
[[Category: Crevel, I.M.-T]]
[[Category: Dna]]
[[Category: Isomerase]]
[[Category: Quinolone]]
[[Category: Topoisomerase iv]]

Revision as of 15:25, 14 September 2016

Quinazolinedione(PD 0305970)-DNA cleavage complex of topoisomerase IV from S. pneumoniae

4z4q, resolution 3.04Å

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