4z53: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 4z53 is ~~ON HOLD until Paper Publication~~

==Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae==

~~Authors~~: ~~Laponogov~~, I., ~~Veselkov~~, D.A.~~, Pan, X~~.-S., ~~Selvarajah~~, J., ~~Crevel, I~~.M.-T., ~~Fisher, L~~.M., ~~Sanderson, M~~.R.

== Structural highlights ==

<table><tr><td colspan='2'>[[4z53]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z53 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z53 FirstGlance].

~~Description~~: ~~Quinolone(Trovafloxacin)-~~DNA ~~cleavage complex~~ of ~~topoisomerase IV from S~~. ~~pneumoniae~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TR6:TROVAFLOXACIN'>TR6</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

[[Category: Fisher, L.M]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z53 OCA], [http://pdbe.org/4z53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z53 RCSB], [http://www.ebi.ac.uk/pdbsum/4z53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z53 ProSAT]</td></tr>

[[Category: Pan, X.-S]]

</table>

[[Category: Sanderson, M.R]]

== Function ==

[[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Crevel, I M.T]]

[[Category: Fisher, L M]]

[[Category: Laponogov, I]]

[[Category: Pan, X S]]

[[Category: Sanderson, M R]]

[[Category: Selvarajah, J]]

[[Category: Veselkov, D.A]]

[[Category: Veselkov, D A]]

[[Category: ~~Laponogov, I~~]]

[[Category: Cleavage complex]]

[[Category: ~~Crevel, I.M.-T~~]]

[[Category: Dna]]

[[Category: Isomerase]]

[[Category: Quinolone]]

[[Category: Topo iv]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4z53 is ON HOLD  until Paper Publication
+==Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae==
+<StructureSection load='4z53' size='340' side='right' caption='[[4z53]], [[Resolution|resolution]] 3.26&Aring;' scene=''>
-Authors: Laponogov, I., Veselkov, D.A., Pan, X.-S., Selvarajah, J., Crevel, I.M.-T., Fisher, L.M., Sanderson, M.R.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4z53]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z53 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z53 FirstGlance]. <br>
-Description: Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TR6:TROVAFLOXACIN'>TR6</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4koe|4koe]], [[4pxp|4pxp]], [[3rad|3rad]], [[3rae|3rae]], [[3raf|3raf]], [[3ksb|3ksb]], [[3ksa|3ksa]], [[4i3h|4i3h]]</td></tr>
-[[Category: Fisher, L.M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z53 OCA], [http://pdbe.org/4z53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z53 RCSB], [http://www.ebi.ac.uk/pdbsum/4z53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z53 ProSAT]</span></td></tr>
-[[Category: Pan, X.-S]]
+</table>
-[[Category: Sanderson, M.R]]
+== Function ==
+[[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Crevel, I M.T]]
+[[Category: Fisher, L M]]
+[[Category: Laponogov, I]]
+[[Category: Pan, X S]]
+[[Category: Sanderson, M R]]
 [[Category: Selvarajah, J]]
-[[Category: Veselkov, D.A]]
+[[Category: Veselkov, D A]]
-[[Category: Laponogov, I]]
+[[Category: Cleavage complex]]
-[[Category: Crevel, I.M.-T]]
+[[Category: Dna]]
+[[Category: Isomerase]]
+[[Category: Quinolone]]
+[[Category: Topo iv]]