5e8d: Difference between revisions

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'''Unreleased structure'''
==Crystal structure of human epiregulin in complex with the Fab fragment of murine monoclonal antibody 9E5==
 
<StructureSection load='5e8d' size='340' side='right' caption='[[5e8d]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
The entry 5e8d is ON HOLD  until Oct 14 2017
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5e8d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E8D FirstGlance]. <br>
Authors: Kado, Y., Mizohata, E., Nagatoishi, S., Iijima, M., Shinoda, K., Miyafusa, T., Nakayama, T., Yoshizumi, T., Sugiyama, A., Kawamura, T., Lee, Y.H., Matsumura, H., Doi, H., Fujitani, H., Kodama, T., Shibasaki, Y., Tsumoto, K., Inoue, T.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5az2|5az2]]</td></tr>
Description: Crystal structure of human epiregulin in complex with the Fab fragment of murine monoclonal antibody 9E5
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e8d OCA], [http://pdbe.org/5e8d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e8d RCSB], [http://www.ebi.ac.uk/pdbsum/5e8d PDBsum]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/EREG_HUMAN EREG_HUMAN]] Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.<ref>PMID:9419975</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Mus musculus]]
[[Category: Doi, H]]
[[Category: Fujitani, H]]
[[Category: Fujitani, H]]
[[Category: Iijima, M]]
[[Category: Inoue, T]]
[[Category: Inoue, T]]
[[Category: Shinoda, K]]
[[Category: Kado, Y]]
[[Category: Doi, H]]
[[Category: Iijima, M]]
[[Category: Shibasaki, Y]]
[[Category: Kawamura, T]]
[[Category: Kawamura, T]]
[[Category: Miyafusa, T]]
[[Category: Kodama, T]]
[[Category: Kodama, T]]
[[Category: Lee, Y H]]
[[Category: Matsumura, H]]
[[Category: Matsumura, H]]
[[Category: Yoshizumi, T]]
[[Category: Miyafusa, T]]
[[Category: Kado, Y]]
[[Category: Mizohata, E]]
[[Category: Nagatoishi, S]]
[[Category: Nagatoishi, S]]
[[Category: Mizohata, E]]
[[Category: Tsumoto, K]]
[[Category: Nakayama, T]]
[[Category: Nakayama, T]]
[[Category: Shibasaki, Y]]
[[Category: Shinoda, K]]
[[Category: Sugiyama, A]]
[[Category: Sugiyama, A]]
[[Category: Lee, Y.H]]
[[Category: Tsumoto, K]]
[[Category: Yoshizumi, T]]
[[Category: Antibody]]
[[Category: Cancer]]
[[Category: Epidermal growth factor]]
[[Category: Immune system]]
[[Category: Immunoglobulin]]
[[Category: Monoclonal antibody]]
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