1a7s: Difference between revisions
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{{STRUCTURE_1a7s| PDB=1a7s | SCENE= }} | |||
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'''ATOMIC RESOLUTION STRUCTURE OF HBP''' | '''ATOMIC RESOLUTION STRUCTURE OF HBP''' | ||
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[[Category: Kastrup, J S.]] | [[Category: Kastrup, J S.]] | ||
[[Category: Larsen, I K.]] | [[Category: Larsen, I K.]] | ||
[[Category: | [[Category: Endotoxin binding]] | ||
[[Category: | [[Category: Heparin]] | ||
[[Category: | [[Category: Serine protease homolog]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 09:56:34 2008'' | |||
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Revision as of 06:56, 2 May 2008
ATOMIC RESOLUTION STRUCTURE OF HBP
Overview
Crystals of human heparin binding protein (HBP) diffract to 1.1 A when flash-frozen at 120 K. The atomic resolution structure has been refined anisotropically using SHELXL96. The final model of HBP consists of 221 amino-acid residues of 225 possible, three glycosylation units, one chloride ion, 15 precipitant ethanol molecules and 323 water molecules. The structure is refined to a final crystallographic R factor of 15.9% and Rfree(5%) of 18.9% using all data. A putative protein kinase C activation site has been identified, involving residues 113-120. The structure is compared to the previously determined 2.3 A resolution structure of HBP.
About this Structure
1A7S is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Atomic resolution structure of human HBP/CAP37/azurocidin., Karlsen S, Iversen LF, Larsen IK, Flodgaard HJ, Kastrup JS, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):598-609. PMID:9761855 Page seeded by OCA on Fri May 2 09:56:34 2008
