Sandbox 77: Difference between revisions
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==5-HT3 receptor antagonist: 4i (N-(3-chloro-2-methylphenyl)quinoxalin-2-carboxamide)== | ==5-HT3 receptor antagonist: 4i (N-(3-chloro-2-methylphenyl)quinoxalin-2-carboxamide)== | ||
A 5HT3 antagonist shown to act as an antidepressant in diabetes-induced depression in mice; it resulted in a significant decrease in 5HT in the midbrain after administration <ref>Gupta D, Devadoss T, Mahesh R. "A novel 5HT 3 antagonist 4i (N-(3-chloro-2-methylphenyl) quinoxalin-2-carboxamide) prevents diabetes-induced depressive phenotypes in mice: Modulation of serotonergic system." Behavioural brain research 297 (2016): 41-50. [http://www.sciencedirect.com/science/article/pii/S0166432815302217 DOI:10.1016/j.bbr.2015.10.007]</ref> | A 5HT3 antagonist shown to act as an antidepressant in diabetes-induced depression in mice; it resulted in a significant decrease in 5HT in the midbrain after administration. <ref>Gupta D, Devadoss T, Mahesh R. "A novel 5HT 3 antagonist 4i (N-(3-chloro-2-methylphenyl) quinoxalin-2-carboxamide) prevents diabetes-induced depressive phenotypes in mice: Modulation of serotonergic system." Behavioural brain research 297 (2016): 41-50. [http://www.sciencedirect.com/science/article/pii/S0166432815302217 DOI:10.1016/j.bbr.2015.10.007]</ref> | ||
==References== | ==References== | ||
