Caffeine: Difference between revisions

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Adenosine is an inhibitory neurotransmitter, which promotes sleep and inhibits arousal. It has two components; an adenine nucleotide and a ribose sugar. Adenosine is a polar molecule and is water soluble. Within the brain, concentration of this neuromodulator increases every hour. Adenosine binds intracellularly to G-protein and induces multiple effects. As adenosine receptors bind G-protein, neural activity begins to decrease and the person feels fatigued and sleepy. A2A receptor is one of many adenosine G protein-coupled receptors (Huang ''et al'' 2014).
Adenosine is an inhibitory neurotransmitter, which promotes sleep and inhibits arousal. It has two components; an adenine nucleotide and a ribose sugar. Adenosine is a polar molecule and is water soluble. Within the brain, concentration of this neuromodulator increases every hour. Adenosine binds intracellularly to G-protein and induces multiple effects. As adenosine receptors bind G-protein, neural activity begins to decrease and the person feels fatigued and sleepy. A2A receptor is one of many adenosine G protein-coupled receptors (Huang ''et al'' 2014).


<scene name='71/716555/Antagonist_binding/4'>A2A Receptor with Adenosine bound</scene>
<scene name='71/716555/Antagonist_binding/5'>A2A Receptor with Adenosine bound</scene>


== Four Different Adenosine Receptors ==
== Four Different Adenosine Receptors ==