5ey0: Difference between revisions
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==Crystal structure of CodY from Staphylococcus aureus with GTP and Ile== | |||
<StructureSection load='5ey0' size='340' side='right' caption='[[5ey0]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ey0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EY0 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=ILE:ISOLEUCINE'>ILE</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ey1|5ey1]], [[5ey2|5ey2]]</td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ey0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ey0 OCA], [http://pdbe.org/5ey0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ey0 RCSB], [http://www.ebi.ac.uk/pdbsum/5ey0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ey0 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CODY_STAA1 CODY_STAA1]] DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Han, A]] | [[Category: Han, A]] | ||
[[Category: Hwang, K Y]] | |||
[[Category: Gtp-sensing]] | |||
[[Category: Pleiotropic transcription regulator]] | |||
[[Category: Transcription]] | |||
Revision as of 15:30, 14 September 2016
Crystal structure of CodY from Staphylococcus aureus with GTP and Ile
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