Cutinase

spinqualitylabelsall models Structure of cutinase complex with inhibitor hexylphosphonate ethyl ester (PDB entry 1xzl) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Cutinase (CUT) catalyzes the conversion of cutin to cutin monomers. Cutin is a main component of the plant cuticle. Polymeric cutin which is composed of hydroxyl and hydroxyepoxy fatty acids is found in the outer layer of plants. CUT is found in fungi and bacteria. CUT degrades the cutin enabling pathogens’ penetration into plant cells. CUT is inhibited by organophosphates like E600 (diethyl-p-nitrophenyl phosphate) and organophosphonates. Relevance Inhibition of CUT can prevent fungal plant infection.

3D Structures of cutinase

Updated on 16-December-2015

{"openlevels":0}

• Cutinase
  • 1cus, 2cut, 1oxm, 1cex, 1agy, 3qpa – NhCUT – Nectria haematococca
    
  • 1ffa, 1ffb, 1ffc, 1ffd, 1ffe, 1cua, 1cub, 1cuc, 1cud, 1cue, 1cuf, 1cug, 1cuh, 1cui, 1cuj, 1cuu, 1cuv, 1cuw, 1cux, 1cuy, 1cuz, 1xza, 1xzb, 1xzc, 1xzd, 1xze, 1xzf, 1xzg, 1xzh, 1xzi, 1xzj – NhCUT (mutant)
    
  • 3dcn – GcCUT – Glomerella cingulata
    
  • 3gbs – CUT – Aspergillus oryzae
    
  • 3esc – CUT – Fusarium solani
    
  • 4cg1, 4cg2, 4cg3 – CUT – Thermobifida fusca
    
  • 4oyy – HiCUT – Humicola insolens
    
  • 4wfi, 4wfj, 4wfk – CUT (mutant) – Sacchromonospora viridis
    
• Cutinase complex with inhibitor
  • 1xzl – NhCUT + hexylphosphonate ethyl ester
    
  • 1xzk – NhCUT + di-isopropyl phosphate
    
  • 1xzm – NhCUT + undecyl chloro phosphonate ester
    
  • 3dd5 – GcCUT + E600
    
  • 3dea – GcCUT + PETFP
    
  • 3ef3, 3esa, 3esb, 3eac, 3esd – NhCUT + Pt inhibitor
    
  • 3qpc – NhCUT + paraoxon
    
  • 3qpd – NhCUT + phosphoserine
    
  • 4oyl – HiCUT + ethyl phosphate
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky