|
|
| Line 1: |
Line 1: |
|
| |
|
| |
|
| <StructureSection load='1vin' size='350' side='right' caption='Cyclin A3 (PDB entry [[1vin]])' scene=''> | | <StructureSection load='1vin' size='350' side='right' caption='Cyclin A3 (PDB entry [[1vin]])' scene=''> |
|
| |
|
| '''Cyclin''' (CYC) activates CYC-dependent kinase (CDK) thus acting in the control of the cell cycle. The CYC name derives from the fact that their concentration varies during the cell cycle. Among the CYCs, '''CYCA''' are active in the S phase, '''CYCD''' regulate the transition from G1 to S.<ref>PMID:11742345</ref> See also [[Intrinsically Disordered Protein]]. | | '''Cyclin''' (CYC) activates CYC-dependent kinase (CDK) thus acting in the control of the cell cycle. The CYC name derives from the fact that their concentration varies during the cell cycle. Among the CYCs, '''CYCA''' is active in the S phase, '''CYCD''' regulate the transition from G1 to S.<ref>PMID:11742345</ref> See also [[Intrinsically Disordered Protein]]. |
|
| |
|
|
| |
|
Revision as of 09:49, 16 December 2015
|
Cyclin (CYC) activates CYC-dependent kinase (CDK) thus acting in the control of the cell cycle. The CYC name derives from the fact that their concentration varies during the cell cycle. Among the CYCs, CYCA is active in the S phase, CYCD regulate the transition from G1 to S.[1] See also Intrinsically Disordered Protein.
- ↑ Larsen NA, Turner JM, Stevens J, Rosser SJ, Basran A, Lerner RA, Bruce NC, Wilson IA. Crystal structure of a bacterial cocaine esterase. Nat Struct Biol. 2002 Jan;9(1):17-21. PMID:11742345 doi:10.1038/nsb742
|
3D Structures of Cyclin
Updated on 16-December-2015
{"openlevels":0}
- CYCA2
- Intrinsically Disordered Protein, 2wpa, 2wxv, 2wih, 2wip, 3f5x, 3eoc, 3eid, 3ej1, 3dog, 3ddp, 3ddq, 3bht, 2v22, 2uue, 2i40, 2bkz, 2c5n, 2c5o, 2c5v, 2c5x, 2c5y, 2bpm, 2c4g, 1fvv, 2c6t – hCYCA2 +CDK2+inhibitor - human
- 3bhu, 3bhv, 2uzd, 2uzb, 2uze, 2uzl, 2uzn, 2uzo, 2iw6, 2iw8, 2iw9, 2g9x, 1oi9, 1oiu, 1oiy, 1ogu, 1p5e, 1pkd, 1h1p, 1h1q, 1h1r, 1h1s, 4cfx, 4cfv, 4cfu, 4cfm - hCYCA2 +CDK2 T160P+inhibitor
- 1fin - hCYCA2 +CDK2
- 1vyw - hCYCA2 C-terminal + hCDK2
- 1jst, 3tnw - hCYCA2 +CDK2 T160P
- 1h24, 1h25, 1h26, 1h27, 1h28, 1gy3 - hCYCA2 +CDK2 T160P+peptide
- 4bck, 4bcm, 4bcn, 4bco, 4bcp, 4bcq, 4cfn, 4cfw - hCYCA2 +CDK2 T160P + inhibitor
- 4fx3 - hCYCA2 +CDK2 + inhibitor
- 4eoi, 4eoj, 4eok, 4eol, 4eom, 4eon, 4eoo, 4eop, 4eoq, 4eor, 4eos - hCYCA2 C-terminal +CDK2 T160P + inhibitor
- 2cjm - hCYCA2 +CDK2 T160P Y15P
- 2cch - hCYCA2 +CDK2 T160P+ATP analog
- 4i3z, 4ii5 - hCYCA2 +CDK2 T160P+ADP + Mg
- 2cci - hCYCA2 +CDK2 T160P+CDC homolog
- 2wma, 2wmb, 2x1n, 2wev, 2wfy, 2whb, 1okv, 1okw, 1ol1, 1ol2, 1urc, 1qmz, 3qhw - hCYCA2 +CDK2+peptide
- 1jsu - hCYCA2 +CDK2 (mutant)+P27
- 3qhr, 3khw - CYCA2 + P33 protein kinase + CDK2 peptide – mouse
- CYCA3
- 1vin – CYCA3 - bovine
- 1e9h – hCYCA3 +CDK2 T160P+inhibitor
- CYCB1
- 2b9r – hCYCB1 (mutant)
- 2jgz - hCYCB1 +CDK2
- CYCC
- CYCD
- CYCE
- 1w98 – hCYCE1 +CDK2 T160P
- CYCH
- CYCK
- 2i53 – hCYCK N-terminal
- 4un0 - hCYCK + CDK12 T160P
- 4cxa - hCYCK + CDK12 T160P + AMPPNP
- 4cjy - hCYCK +CDK12 T160P+inhibitor
- CYCT
- 3blh - hCYCT1 +CDK9
- 3blq - hCYCT1 +CDK9+ATP
- 4imy - hCYCT1 +CDK9 TPO160 +AMP + AF4/MRF2 family member 4
- 3lq5, 3tn8, 3tnh, 3tni, 4bcf, 4bcg, 4bch, 4bci, 4bcj – hCYCT1 (mutant)+CDK9
- 3blr - hCYCT1 +CDK9+inhibitor
- 3my1, 4ec8, 4ec9 - hCYCT1 (mutant)+CDK9 TPO160 +inhibitor
- 3mi9, 3mia - hCYCT1 +CDK9+protein TAT
- 2w2h - CYCT1 +protein TAT + RNA – horse
- 2ivx – hCYCT2 (mutant)
- CYC
- 2pk9 – yCYC PHO80 +CDK PHO85 – yeast
- 2pmi - yCYC PHO80 +CDK PHO85+ATPgS
- Viral CYC
- 2euf, 2f2c, 2xo2, 1jow – V-CYC viral+hCDK6 – Herpesvirus
- 1bu2 – V-CYC
- 1xo2 - V-CYC + hCDK6 + inhibitor
- 1g3n - V-CYC viral+hCDK6+CDK6 inhibitor
- 1f5q - V-CYC g viral+hCDK2
References
proteopedia link