Cyclin: Difference between revisions

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<StructureSection load='3blh' size='350' side='right' caption='Cyclin A3 (PDB entry [[1vin]])' scene=''>
== Function ==


<StructureSection load='1vin' size='350' side='right' caption='Cyclin A3 (PDB entry [[1vin]])' scene=''>
'''Cyclin''' (CYC) activates CYC-dependent kinase (CDK) thus acting in the control of the cell cycle.  The CYC name derives from the fact that different CYCs are expressed during different phases of the cell cycle.  Among the CYCs, '''CYCA''' is active in the S phase, '''CYCD''' regulate the transition from G1 to S.<ref>PMID:12910258</ref>  See also [[Intrinsically Disordered Protein]].
 
'''Cyclin''' (CYC) activates CYC-dependent kinase (CDK) thus acting in the control of the cell cycle.  The CYC name derives from the fact that their concentration varies during the cell cycle.  Among the CYCs, '''CYCA''' is active in the S phase, '''CYCD''' regulate the transition from G1 to S.<ref>PMID:11742345</ref>  See also [[Intrinsically Disordered Protein]].


== Structural highlights ==


All cyclins have an all-α helix fold and share an identical ca. 100 residue domain called 'cyclin box' which binds CDK.


</StructureSection>
</StructureSection>
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