5bzq: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5bzq is ~~ON HOLD until Paper Publication~~

==Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule==

~~Authors~~: ~~Liu~~, L.K., ~~Finzel~~, B.C.

== Structural highlights ==

<table><tr><td colspan='2'>[[5bzq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BZQ FirstGlance]. <br>

~~Description: Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4XL:2-[3-(MORPHOLIN-4-YL)PROPYL]-1,2,3,4-TETRAHYDROISOQUINOLIN-8-AMINE'>4XL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzq OCA], [http://pdbe.org/5bzq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bzq RCSB], [http://www.ebi.ac.uk/pdbsum/5bzq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzq ProSAT]</span></td></tr>

[[Category: Finzel, B.C]]

</table>

[[Category: Liu, L.K]]

== Function ==

[[http://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE]] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.

__TOC__

</StructureSection>

[[Category: Finzel, B C]]

[[Category: Liu, L K]]

[[Category: Link module]]

[[Category: Protein binding]]

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-'''Unreleased structure'''
-The entry 5bzq is ON HOLD  until Paper Publication
+==Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule==
+<StructureSection load='5bzq' size='340' side='right' caption='[[5bzq]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
-Authors: Liu, L.K., Finzel, B.C.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5bzq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BZQ FirstGlance]. <br>
-Description: Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4XL:2-[3-(MORPHOLIN-4-YL)PROPYL]-1,2,3,4-TETRAHYDROISOQUINOLIN-8-AMINE'>4XL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzq OCA], [http://pdbe.org/5bzq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bzq RCSB], [http://www.ebi.ac.uk/pdbsum/5bzq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzq ProSAT]</span></td></tr>
-[[Category: Finzel, B.C]]
+</table>
-[[Category: Liu, L.K]]
+== Function ==
+[[http://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE]] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.
+__TOC__
+</StructureSection>
+[[Category: Finzel, B C]]
+[[Category: Liu, L K]]
+[[Category: Link module]]
+[[Category: Protein binding]]