5cvc: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5cvc is ~~ON HOLD until Paper~~ Publication

==Structure of maize serine racemase==

== Structural highlights ==

<table><tr><td colspan='2'>[[5cvc]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CVC FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cvc OCA], [http://pdbe.org/5cvc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cvc RCSB], [http://www.ebi.ac.uk/pdbsum/5cvc PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

Serine racemase (SR) is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that is responsible for D-serine biosynthesis in vivo. The first X-ray crystal structure of maize SR was determined to 2.1 A resolution and PLP binding was confirmed in solution by UV-Vis absorption spectrometry. Maize SR belongs to the type II PLP-dependent enzymes and differs from the SR of a vancomycin-resistant bacterium. The PLP is bound to each monomer by forming a Schiff base with Lys67. Structural comparison with rat and fission yeast SRs reveals a similar arrangement of active-site residues but a different orientation of the C-terminal helix.

~~Authors:~~ Song, Y., ~~Zou~~, L., Fan, J.

Crystal structure of maize serine racemase with pyridoxal 5'-phosphate.,Zou L, Song Y, Wang C, Sun J, Wang L, Cheng B, Fan J Acta Crystallogr F Struct Biol Commun. 2016 Mar 1;72(Pt 3):165-71. doi:, 10.1107/S2053230X16000960. Epub 2016 Feb 16. PMID:26919519<ref>PMID:26919519</ref>

~~Description: Structure~~ of ~~maize serine racemase~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

~~[[Category~~: ~~Unreleased Structures]]~~

</div>

~~[[Category: Zou, L]]~~

== References ==

__TOC__

</StructureSection>

[[Category: Fan, J]]

[[Category: Song, Y]]

[[Category: Zou, L]]

[[Category: Isomerase]]

[[Category: Maize serine racemase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5cvc is ON HOLD  until Paper Publication
+==Structure of maize serine racemase==
+<StructureSection load='5cvc' size='340' side='right' caption='[[5cvc]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5cvc]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CVC FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cvc OCA], [http://pdbe.org/5cvc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cvc RCSB], [http://www.ebi.ac.uk/pdbsum/5cvc PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Serine racemase (SR) is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that is responsible for D-serine biosynthesis in vivo. The first X-ray crystal structure of maize SR was determined to 2.1 A resolution and PLP binding was confirmed in solution by UV-Vis absorption spectrometry. Maize SR belongs to the type II PLP-dependent enzymes and differs from the SR of a vancomycin-resistant bacterium. The PLP is bound to each monomer by forming a Schiff base with Lys67. Structural comparison with rat and fission yeast SRs reveals a similar arrangement of active-site residues but a different orientation of the C-terminal helix.
-Authors: Song, Y., Zou, L., Fan, J.
+Crystal structure of maize serine racemase with pyridoxal 5'-phosphate.,Zou L, Song Y, Wang C, Sun J, Wang L, Cheng B, Fan J Acta Crystallogr F Struct Biol Commun. 2016 Mar 1;72(Pt 3):165-71. doi:, 10.1107/S2053230X16000960. Epub 2016 Feb 16. PMID:26919519<ref>PMID:26919519</ref>
-Description: Structure of maize serine racemase
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>
-[[Category: Zou, L]]
+<div class="pdbe-citations 5cvc" style="background-color:#fffaf0;"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Fan, J]]
 [[Category: Song, Y]]
+[[Category: Zou, L]]
+[[Category: Isomerase]]
+[[Category: Maize serine racemase]]