5dxx: Difference between revisions
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==Crystal structure of Dbr2== | |||
<StructureSection load='5dxx' size='340' side='right' caption='[[5dxx]], [[Resolution|resolution]] 1.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5dxx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DXX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DXX FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dxy|5dxy]], [[5dy2|5dy2]], [[5dy3|5dy3]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Artemisinic_aldehyde_Delta(11(13))_reductase Artemisinic aldehyde Delta(11(13)) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.92 1.3.1.92] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dxx OCA], [http://pdbe.org/5dxx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dxx RCSB], [http://www.ebi.ac.uk/pdbsum/5dxx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dxx ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DBR2_ARTAN DBR2_ARTAN]] Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent.<ref>PMID:18495659</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chen, T T]] | |||
[[Category: Li, L]] | [[Category: Li, L]] | ||
[[Category: | [[Category: Xu, Y C]] | ||
[[Category: | [[Category: Dbr2]] | ||
[[Category: Oxidoreductase]] | |||
