5e2n: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5e2n is ON HOLD until Paper Publication~~

==Crystal structure of human carbonic anhydrase isozyme XIII with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide==

~~Authors: Manakova, E., Smirnov, A., Grazulis, S.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5e2n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E2N OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E2N FirstGlance].

~~Description:~~ Crystal structure of human carbonic anhydrase isozyme XIII with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=V14:3-(CYCLOOCTYLAMINO)-2,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL)SULFONYL]BENZENESULFONAMIDE'>V14</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e2n OCA], [http://pdbe.org/5e2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e2n RCSB], [http://www.ebi.ac.uk/pdbsum/5e2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e2n ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CAH13_HUMAN CAH13_HUMAN]] Reversible hydration of carbon dioxide.

__TOC__

</StructureSection>

[[Category: Carbonate dehydratase]]

[[Category: Grazulis, S]]

[[Category: Manakova, E]]

~~[[Category: Grazulis, S]]~~

[[Category: Smirnov, A]]

[[Category: Benzenesulfonamide]]

[[Category: Carbonic anhydrase]]

[[Category: Drug design]]

[[Category: Lyase]]

[[Category: Lyase-lyase inhibitor complex]]

[[Category: Metal-binding]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5e2n is ON HOLD  until Paper Publication
+==Crystal structure of human carbonic anhydrase isozyme XIII with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide==
+<StructureSection load='5e2n' size='340' side='right' caption='[[5e2n]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
-Authors: Manakova, E., Smirnov, A., Grazulis, S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5e2n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E2N FirstGlance]. <br>
-Description: Crystal structure of human carbonic anhydrase isozyme XIII with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=V14:3-(CYCLOOCTYLAMINO)-2,5,6-TRIFLUORO-4-[(2-HYDROXYETHYL)SULFONYL]BENZENESULFONAMIDE'>V14</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dog|5dog]], [[5doh|5doh]], [[5drs|5drs]], [[5e2m|5e2m]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e2n OCA], [http://pdbe.org/5e2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e2n RCSB], [http://www.ebi.ac.uk/pdbsum/5e2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e2n ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CAH13_HUMAN CAH13_HUMAN]] Reversible hydration of carbon dioxide.
+__TOC__
+</StructureSection>
+[[Category: Carbonate dehydratase]]
+[[Category: Grazulis, S]]
 [[Category: Manakova, E]]
-[[Category: Grazulis, S]]
 [[Category: Smirnov, A]]
+[[Category: Benzenesulfonamide]]
+[[Category: Carbonic anhydrase]]
+[[Category: Drug design]]
+[[Category: Lyase]]
+[[Category: Lyase-lyase inhibitor complex]]
+[[Category: Metal-binding]]