5e51: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5e51 is ~~ON HOLD until Paper Publication~~

==Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 1 with Faropenem adduct==

~~Authors~~: ~~Kumar~~, P., ~~Lamichhane~~, G., ~~Ginell~~, S.L.

== Structural highlights ==

<table><tr><td colspan='2'>[[5e51]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E51 FirstGlance]. <br>

~~Description~~: ~~Crystal structure~~ of ~~Mycobacterium tuberculosis L,~~D-~~transpeptidase 1 with Faropenem adduct~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5KO:(3R)-3-HYDROXYBUTANAL'>5KO</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e51 OCA], [http://pdbe.org/5e51 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e51 RCSB], [http://www.ebi.ac.uk/pdbsum/5e51 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e51 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/LDT1_MYCTO LDT1_MYCTO]] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems (By similarity).

__TOC__

</StructureSection>

[[Category: Ginell, S L]]

[[Category: Kumar, P]]

~~[[Category: Ginell, S.L]]~~

[[Category: Lamichhane, G]]

[[Category: Cell wall enzyme]]

[[Category: D-transpeptidase 1]]

[[Category: Ldtmt1]]

[[Category: Mycobacterium tuberculosis]]

[[Category: Peptidoglycan synthesis enzyme]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5e51 is ON HOLD  until Paper Publication
+==Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 1 with Faropenem adduct==
+<StructureSection load='5e51' size='340' side='right' caption='[[5e51]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-Authors: Kumar, P., Lamichhane, G., Ginell, S.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5e51]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E51 FirstGlance]. <br>
-Description: Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 1 with Faropenem adduct
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5KO:(3R)-3-HYDROXYBUTANAL'>5KO</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e51 OCA], [http://pdbe.org/5e51 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e51 RCSB], [http://www.ebi.ac.uk/pdbsum/5e51 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e51 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/LDT1_MYCTO LDT1_MYCTO]] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Ginell, S L]]
 [[Category: Kumar, P]]
-[[Category: Ginell, S.L]]
 [[Category: Lamichhane, G]]
+[[Category: Cell wall enzyme]]
+[[Category: D-transpeptidase 1]]
+[[Category: Ldtmt1]]
+[[Category: Mycobacterium tuberculosis]]
+[[Category: Peptidoglycan synthesis enzyme]]
+[[Category: Transferase]]