5acc: Difference between revisions
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==A Novel Oral Selective Estrogen Receptor Down-regulator, AZD9496, drives Tumour Growth Inhibition in Estrogen Receptor positive and ESR1 Mutant Models== | ==A Novel Oral Selective Estrogen Receptor Down-regulator, AZD9496, drives Tumour Growth Inhibition in Estrogen Receptor positive and ESR1 Mutant Models== | ||
<StructureSection load='5acc' size='340' side='right' caption='[[5acc]], [[Resolution|resolution]] 1.88Å' scene=''> | <StructureSection load='5acc' size='340' side='right'caption='[[5acc]], [[Resolution|resolution]] 1.88Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5acc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ACC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ACC FirstGlance]. <br> | <table><tr><td colspan='2'>[[5acc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ACC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ACC FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KE9:(E)-3-(3,5-DIFLUORO-4-((1R,3R)-2-(2-FLUORO-2-+METHYLPROPYL)-3-METHYL-2,3,4,9-TETRAHYDRO-1H-PYRIDO(3,4-B)INDOL-1-YL)PHENYL)ACRYLIC+ACID'>KE9</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KE9:(E)-3-(3,5-DIFLUORO-4-((1R,3R)-2-(2-FLUORO-2-+METHYLPROPYL)-3-METHYL-2,3,4,9-TETRAHYDRO-1H-PYRIDO(3,4-B)INDOL-1-YL)PHENYL)ACRYLIC+ACID'>KE9</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5acc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5acc OCA], [http://pdbe.org/5acc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5acc RCSB], [http://www.ebi.ac.uk/pdbsum/5acc PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5acc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5acc OCA], [http://pdbe.org/5acc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5acc RCSB], [http://www.ebi.ac.uk/pdbsum/5acc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5acc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5acc" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5acc" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Estrogen receptor 3D structures|Estrogen receptor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Almeida, C de]] | [[Category: Almeida, C de]] | ||
[[Category: Ballard, P]] | [[Category: Ballard, P]] | ||
