2na0: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

==NMR structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) mutant V77E in a Ca2+-free/Mg2+-bound Activator State==

~~The entry 2na0 is ON HOLD~~

== Structural highlights ==

<table><tr><td colspan='2'>[[2na0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NA0 FirstGlance]. <br>

~~Authors: Lim, S., Ames, J.B.~~

</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2na0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2na0 OCA], [http://pdbe.org/2na0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2na0 RCSB], [http://www.ebi.ac.uk/pdbsum/2na0 PDBsum]</span></td></tr>

~~Description: Backbone 1H, 13C, and 15N Chemical Shift Assignments~~ of Guanylyl Cyclase Activator Protein 1 (GCAP1) mutant V77E in a Ca2+-free/Mg2+-bound Activator State

</table>

[[~~Category~~: ~~Unreleased Structures~~]]

== Function ==

[[Category: Ames, J.B]]

[[http://www.uniprot.org/uniprot/GUC1A_BOVIN GUC1A_BOVIN]] Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.

__TOC__

</StructureSection>

[[Category: Ames, J B]]

[[Category: Lim, S]]

[[Category: Activator state]]

[[Category: Lyase activator]]

[[Category: Signal transduction]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==NMR structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) mutant V77E in a Ca2+-free/Mg2+-bound Activator State==
+<StructureSection load='2na0' size='340' side='right' caption='[[2na0]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
-The entry 2na0 is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2na0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NA0 FirstGlance]. <br>
-Authors: Lim, S., Ames, J.B.
+</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2na0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2na0 OCA], [http://pdbe.org/2na0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2na0 RCSB], [http://www.ebi.ac.uk/pdbsum/2na0 PDBsum]</span></td></tr>
-Description: Backbone 1H, 13C, and 15N Chemical Shift Assignments of Guanylyl Cyclase Activator Protein 1 (GCAP1) mutant V77E in a Ca2+-free/Mg2+-bound Activator State
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
-[[Category: Ames, J.B]]
+[[http://www.uniprot.org/uniprot/GUC1A_BOVIN GUC1A_BOVIN]] Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
+__TOC__
+</StructureSection>
+[[Category: Ames, J B]]
 [[Category: Lim, S]]
+[[Category: Activator state]]
+[[Category: Lyase activator]]
+[[Category: Signal transduction]]