Defensin: Difference between revisions

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== Relevance ==
== Relevance ==


There is increase in α-DEF in chronic inflammations and several cancers.  DEF-mimetics are developed as antibiotics.
There is increase in α-DEF in chronic inflammations and several cancers.  DEF-mimetics are developed as antibiotics<ref>PMID:2997278</ref>.


== Disease ==
== Disease ==


Overexpression of α-defensin is seen in chronic inflammation, several cancers and in T-cells of schizophrenia patients.
Overexpression of α-defensin is seen in chronic inflammation, several cancers and in T-cells of schizophrenia patients<ref>PMID:25265350</ref>.


== Structural highlights ==
== Structural highlights ==