5ejk: Difference between revisions
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==Crystal structure of the Rous sarcoma virus intasome== | |||
<StructureSection load='5ejk' size='340' side='right' caption='[[5ejk]], [[Resolution|resolution]] 3.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ejk]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EJK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EJK FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=W:TUNGSTEN+ION'>W</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ejk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ejk OCA], [http://pdbe.org/5ejk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ejk RCSB], [http://www.ebi.ac.uk/pdbsum/5ejk PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/POL_RSVP POL_RSVP]] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Aihara, H]] | |||
[[Category: Banerjee, S]] | [[Category: Banerjee, S]] | ||
[[Category: Shi, K]] | [[Category: Shi, K]] | ||
[[Category: Yin, Z]] | [[Category: Yin, Z]] | ||
[[Category: Intasome]] | |||
[[Category: Integrase]] | |||
[[Category: Rsv]] | |||
[[Category: Transferase-dna complex]] | |||
Revision as of 02:55, 21 February 2016
Crystal structure of the Rous sarcoma virus intasome
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