Met repressor: Difference between revisions

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[[Image:1mjo.png|left|200px|thumb|EcMR (mutant) complex with corepressor SAM and DNA  [[2eyi]]]]
{{STRUCTURE_1mjo|  PDB=1mjo  | SIZE=400| SCENE= |right|CAPTION=EcMR (mutant) complex with corepressor SAM Ca+2 ion (green) and DNA [[1mjo]] }}
{{STRUCTURE_1mjo|  PDB=1mjo  | SIZE=400| SCENE= |right|CAPTION=EcMR (mutant) complex with corepressor SAM Ca+2 ion (green) and DNA [[1mjo]] }}
 
== Function ==
 
'''Met repressor''' (MR) interacts with the DNA operator (Met box) repressing methionine synthesis.  The coreppressor of MR is S-adenosyl methionine (SAM) which is a product of methionine synthesis.  Binding of SAM to MR increases the repressor affinity to the DNA thus halting methionine synthesis<ref>PMID:11696548</ref>.  For additional details see<br />
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
'''Met repressor''' (MR) interacts with the DNA operator (Met box) repressing methionine synthesis.  The corepressor of MR is S-adenosyl methionine (SAM) which is a product of methionine synthesis.  Binding of SAM to MR increases the repressor affinity to the DNA thus halting methionine synthesis.  For additional details see<br />
[[Taylor met repressor]]<br />
[[Taylor met repressor]]<br />
[[Joe Granger Methionine Repressor: Escherichia coli]].
[[Joe Granger Methionine Repressor: Escherichia coli]].
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[[1mjl]], [[1mjp]] – EcMR (mutant) + SAM<br />
[[1mjl]], [[1mjp]] – EcMR (mutant) + SAM<br />
[[1mj2]], [[1mjo]], [[1mjq]] – EcMR (mutant) + SAM + DNA<br />
[[1mj2]], [[1mjo]], [[1mjq]] – EcMR (mutant) + SAM + DNA<br />
== References ==
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]