Elastase: Difference between revisions
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{{STRUCTURE_1esa| PDB=1esa | SIZE=400| SCENE= |right|CAPTION= Pig elastase acyl-intermediate complex with sulfate and Ca+2 ion [[1esa]] }} | {{STRUCTURE_1esa| PDB=1esa | SIZE=400| SCENE= |right|CAPTION= Pig elastase acyl-intermediate complex with sulfate and Ca+2 ion [[1esa]] }} | ||
[[Elastase]] (ELA) is a chymotrypsin-like protease which breaks down proteins. The ELAs are numbered according to their genes. | [[Elastase]] (ELA) is a chymotrypsin-like protease which breaks down proteins. The ELAs are numbered according to their genes. Panceatic ELA cleaves proteins at the carboxyl-terminal side of small neutral amino acids. It cleaves Ala-Ala and Ala-Gly bonds. <ref>PMID:12059069</ref> For additional details see [[Serine Proteases]]. | ||
== Relevance == | |||
'''ELA2''' (or PMN-ELA) is secreted by neutrophils during inflammation. | |||
== Disease == | == Disease == | ||
