2na9: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 2na9 is ~~ON HOLD until Paper Publication~~

==Transmembrane Structure of the P441A Mutant of the Cytokine Receptor Common Subunit beta==

~~Authors~~: ~~Schmidt~~, T., Ye, F.~~, Situ, A~~.J., ~~An, W~~.~~, Ginsberg, M~~.H., ~~Ulmer, T~~.S.

== Structural highlights ==

<table><tr><td colspan='2'>[[2na9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NA9 FirstGlance]. <br>

~~Description~~: ~~Transmembrane Structure of~~ the ~~P441A Mutant~~ of ~~the Cytokine Receptor Common Subunit beta~~

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2na8|2na8]]</td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2na9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2na9 OCA], [http://pdbe.org/2na9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2na9 RCSB], [http://www.ebi.ac.uk/pdbsum/2na9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2na9 ProSAT]</span></td></tr>

[[~~Category~~: ~~Ginsberg, M~~.H]]

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] Defects in CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5) [MIM:[http://omim.org/entry/614370 614370]]. SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.<ref>PMID:21075760</ref>

== Function ==

[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.

== References ==

__TOC__

</StructureSection>

[[Category: An, W]]

[[Category: ~~Situ~~, ~~A.J~~]]

[[Category: Ginsberg, M H]]

[[Category: Schmidt, T]]

[[Category: Situ, A J]]

[[Category: Ulmer, T S]]

[[Category: Ye, F]]

[[Category: ~~Ulmer, T.S~~]]

[[Category: Nbp residue]]

[[Category: Signaling protein]]

[[Category: Transmembrane helix]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 2na9 is ON HOLD  until Paper Publication
+==Transmembrane Structure of the P441A Mutant of the Cytokine Receptor Common Subunit beta==
+<StructureSection load='2na9' size='340' side='right' caption='[[2na9]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
-Authors: Schmidt, T., Ye, F., Situ, A.J., An, W., Ginsberg, M.H., Ulmer, T.S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2na9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NA9 FirstGlance]. <br>
-Description: Transmembrane Structure of the P441A Mutant of the Cytokine Receptor Common Subunit beta
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2na8|2na8]]</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2na9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2na9 OCA], [http://pdbe.org/2na9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2na9 RCSB], [http://www.ebi.ac.uk/pdbsum/2na9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2na9 ProSAT]</span></td></tr>
-[[Category: Ginsberg, M.H]]
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] Defects in CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5) [MIM:[http://omim.org/entry/614370 614370]]. SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.<ref>PMID:21075760</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: An, W]]
-[[Category: Situ, A.J]]
+[[Category: Ginsberg, M H]]
 [[Category: Schmidt, T]]
+[[Category: Situ, A J]]
+[[Category: Ulmer, T S]]
 [[Category: Ye, F]]
-[[Category: Ulmer, T.S]]
+[[Category: Nbp residue]]
+[[Category: Signaling protein]]
+[[Category: Transmembrane helix]]