Sandbox Reserved 1124: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 17: | Line 17: | ||
===The SH2 domain=== | ===The SH2 domain=== | ||
<scene name='71/719865/Sh2domains/1'>The SH2 domains</scene> encompasse 8 beta strands (61 to 64 ; 82 to 87 ; 95 to 101 ; 104 to 109 ; 111 to 112 ; 118 to 119 ; 124 to 125 ; 149 - 150) and 2 alpha helices (67 to 74 and 128 to 134). | <scene name='71/719865/Sh2domains/1'>The SH2 domains</scene> encompasse 8 beta strands (61 to 64 ; 82 to 87 ; 95 to 101 ; 104 to 109 ; 111 to 112 ; 118 to 119 ; 124 to 125 ; 149 - 150) and 2 alpha helices (67 to 74 and 128 to 134). The βB, βC and βD strands compose a three-stranded antiparallel β-sheet and the 2 α-helices are positioned on both sides. Moreover, the short parallel βA and βG strands extend the central β-sheet. There are also βD', βE and βF strands which are smaller β-sheet-like structure. | ||
The amino acid in red are residues which are responsible for forming the phosphopeptide binding pocket. In green, this is residues which can bind to the negatively charged phosphorylated tyrosine residue of the binding peptide. | |||
