5hkc: Difference between revisions
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==Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA== | |||
<StructureSection load='5hkc' size='340' side='right' caption='[[5hkc]], [[Resolution|resolution]] 1.68Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5hkc]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HKC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HKC FirstGlance]. <br> | |||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DU:2-DEOXYURIDINE-5-MONOPHOSPHATE'>DU</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hk3|5hk3]], [[5hjz|5hjz]], [[5hk0|5hk0]]</td></tr> | ||
[[Category: Yen, T | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hkc OCA], [http://pdbe.org/5hkc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hkc RCSB], [http://www.ebi.ac.uk/pdbsum/5hkc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hkc ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/MAZF6_MYCTO MAZF6_MYCTO]] Toxic component of a type II toxin-antitoxin (TA) module. Acts as an endoribonuclease on single-strand RNA, cleaving between the second and third bases in the sequences CUCCU and UUCCU. Neutralized by coexpression with cognate antitoxin MazE6.[UniProtKB:P9WII3] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Brennan, R G]] | |||
[[Category: Yen, T J]] | |||
[[Category: Hydrolase-rna complex]] | |||
[[Category: Mazf]] | |||
[[Category: Toxin-antitoxin system]] | |||
Revision as of 00:41, 19 January 2017
Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA
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