Sandbox Reserved 1124: Difference between revisions

<scene name='71/719865/Sh2domains/1'>The SH2 domain</scene> encompasses 8 beta strands (<scene name='71/719865/Beta_strand_61-64/1'>61 to 64</scene> ; <scene name='71/719865/Beta_strand_82-87/1'>82 to 87</scene> ; <scene name='71/719865/Beta_strand_95-101/1'>95 to 101</scene> ; <scene name='71/719865/Beta_strand_104-109/1'>104 to 109</scene> ; <scene name='71/719865/Beta_strand_111-112/1'>111 to 112</scene> ; <scene name='71/719865/Beta_strand_118-119/1'>118 to 119</scene> ; <scene name='71/719865/Beta_strand_124-125/1'>124 to 125</scene> ; <scene name='71/719865/Beta_strand_149-150/2'>149 to 150</scene>) and 2 alpha helices (<scene name='71/719865/Alpha_helix_67-74/1'>67 to 74</scene> and <scene name='71/719865/Alpha_helix_128-134/1'>128 to 134</scene>). The βB, βC and βD strands compose a three-stranded antiparallel β-sheet and the 2 α-helices are positioned on both sides. Moreover, the short parallel βA and βG strands extend the central β-sheet. There are also βD', βE and βF strands which are smaller β-sheet-like structure. <ref>DOI:10.1007/s10858-008-9272-0</ref> [[Image:Sequence_of_the_SH2_domain_of_Grb2.PNG | thumb | upright=3 | Sequence of the SH2 domain (60 to 152 amino acids) of Grb2 <ref name="Kousik">Kousik Kundu In Silico Prediction of Modular Domain-Peptide Interactions (2015) [https://scholar.google.com/citations?view_op=view_citation&hl=en&user=0iOlQDAAAAAJ&citation_for_view=0iOlQDAAAAAJ:qUcmZB5y_30C]</ref>]]