Sandbox Reserved 1125: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Laura Dutto (talk | contribs) No edit summary |
Laura Dutto (talk | contribs) No edit summary |
||
| Line 87: | Line 87: | ||
== Disease == | == Disease == | ||
=== knc === | === knc === | ||
Overexpression of MMP-8, or inadequate control by TIMPs, can be associated with a lot of pathological conditions | Overexpression of MMP-8, or inadequate control by TIMPs, can be associated with a lot of pathological conditions<ref>[http://www.enzim.hu/~lbarna/articles/19173605.pdf "Extra Binding Region Induced by Non-Zinc Chelating Inhibitors into the S1′ Subsite of Matrix Metalloproteinase 8"]</ref>. Moreover, what makes this MMP unique is its exclusive pattern of expression in inflammatory conditions.<ref>PMID:9727011</ref> | ||
*psoriasis, sclerosis, osteoarthritis, rheumatoid arthritis, osteoporosis | |||
*Alzheimer's disease | |||
*tumor growh and metastasis | |||
*(MMP)-8 has been associated with the progression of periodontitis, a common inflammatory disease of the supporting structures of the teeth<ref>PMID:16928431</ref> | *(MMP)-8 has been associated with the progression of periodontitis, a common inflammatory disease of the supporting structures of the teeth<ref>PMID:16928431</ref> | ||
