Sandbox Reserved 1125: Difference between revisions

Revision as of 17:18, 30 January 2016 view source Christophe Toussaint (talk \| contribs) 63 edits No edit summary ← Older edit		Revision as of 17:18, 30 January 2016 view source Christophe Toussaint (talk \| contribs) 63 edits No edit summary Newer edit →
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	===== Zn998 : the structural zinc =====		===== Zn998 : the structural zinc =====
	The residues involved in the Zn998 interactions are <scene name='71/719866/Zn998/2'>an Asp residue (149) next to three His residues (147, 162 and 175)</scene>. The glutamic acid adjacent to the first histidine is essential for catalysis. It should be noted that scientists were unable to exchange or remove this Zinc in their crystals, which is suggesting that there is a tight interaction with MMP-8.<ref name="X-ray"/>		The residues involved in the Zn998 interactions are <scene name='71/719866/Zn998/2'>an Asp residue (149) next to three His residues (147, 162 and 175)</scene>. The glutamic acid adjacent to the first histidine is essential for catalysis. It should be noted that scientists were unable to exchange or remove this Zinc in their crystals, which is suggesting that there is a tight interaction with MMP-8.<ref name="X-ray"/>

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