Sandbox Reserved 1125: Difference between revisions
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''MMP-8'', also called, ''Neutrophil collagenase'' or ''Collagenase 2'', is a zinc-dependent and calcium-dependent enzyme mainly produced by neutrophils. It belongs to the [[Matrix metalloproteinase|matrix metalloproteinase]] (MMP) family which is involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes. The gene coding this family is localized on the chromosome 11 of Homo sapiens with 467 residues.<ref>[http://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=4317 "MMP-8 matrix metallopeptidase 8 (neutrophil collagenase)"]</ref> | ''MMP-8'', also called, ''Neutrophil collagenase'' or ''Collagenase 2'', is a zinc-dependent and calcium-dependent enzyme mainly produced by neutrophils. It belongs to the [[Matrix metalloproteinase|matrix metalloproteinase]] (MMP) family which is involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes. The gene coding this family is localized on the chromosome 11 of Homo sapiens with 467 residues.<ref>[http://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=4317 "MMP-8 matrix metallopeptidase 8 (neutrophil collagenase)"]</ref> | ||
<scene name='71/719866/Reloader/1'>Here</scene> is the reloading for the initial structure of the catalytic domain of MMP-8. | <scene name='71/719866/Reloader/1'>Here</scene> is the reloading for the initial structure of the catalytic domain of MMP-8. ( Protein Data Bank ID : 2OY4 ) | ||
<StructureSection load='2oy4' size='340' side='right' caption='Matrix metalloproteinase-8 catalytic domain' scene='71/719866/Mmp-8/3'> | <StructureSection load='2oy4' size='340' side='right' caption='Matrix metalloproteinase-8 catalytic domain ' scene='71/719866/Mmp-8/3'> | ||
== Classification == | == Classification == | ||
