1c8m: Difference between revisions

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==REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS==

== Structural highlights ==

<table><tr><td colspan='2'>[[1c8m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Hrv-16 Hrv-~~16]. The August 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Poliovirus and Rhinovirus'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_8 10.2210/rcsb_pdb/mom_2001_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8M OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C8M FirstGlance].

<table><tr><td colspan='2'>[[1c8m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_rhinovirus_16 Human rhinovirus 16]. The August 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Poliovirus and Rhinovirus'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_8 10.2210/rcsb_pdb/mom_2001_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8M OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C8M FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=W11:3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE'>W11</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c8m OCA], [http://pdbe.org/1c8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1c8m RCSB], [http://www.ebi.ac.uk/pdbsum/1c8m PDBsum]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c8m OCA], [http://pdbe.org/1c8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1c8m RCSB], [http://www.ebi.ac.uk/pdbsum/1c8m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1c8m ProSAT]</td></tr>

</table>

== Function ==

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__TOC__

</StructureSection>

[[Category: ~~Hrv-~~16]]

[[Category: Human rhinovirus 16]]

[[Category: Poliovirus and Rhinovirus]]

[[Category: RCSB PDB Molecule of the Month]]

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[[Category: Antiviral compound]]

[[Category: Drug]]

~~[[Category: Human rhinovirus 16]]~~

[[Category: Icosahedral virus]]

[[Category: Rhinovirus coat protein]]

[[Category: Virus]]

[[Category: Win compound]]

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 ==REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS==
 <StructureSection load='1c8m' size='340' side='right' caption='[[1c8m]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1c8m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hrv-16 Hrv-16]. The August 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Poliovirus and Rhinovirus''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_8 10.2210/rcsb_pdb/mom_2001_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C8M FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1c8m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_rhinovirus_16 Human rhinovirus 16]. The August 2001 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Poliovirus and Rhinovirus''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_8 10.2210/rcsb_pdb/mom_2001_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C8M FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=W11:3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE'>W11</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ayn|1ayn]], [[1aym|1aym]], [[1qju|1qju]], [[1qjx|1qjx]], [[1qjy|1qjy]]</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c8m OCA], [http://pdbe.org/1c8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1c8m RCSB], [http://www.ebi.ac.uk/pdbsum/1c8m PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c8m OCA], [http://pdbe.org/1c8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1c8m RCSB], [http://www.ebi.ac.uk/pdbsum/1c8m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1c8m ProSAT]</span></td></tr>
 </table>
 == Function ==
@@ Line 21: / Line 22: @@
 __TOC__
 </StructureSection>
-[[Category: Hrv-16]]
+[[Category: Human rhinovirus 16]]
 [[Category: Poliovirus and Rhinovirus]]
 [[Category: RCSB PDB Molecule of the Month]]
@@ Line 31: / Line 32: @@
 [[Category: Antiviral compound]]
 [[Category: Drug]]
-[[Category: Human rhinovirus 16]]
 [[Category: Icosahedral virus]]
 [[Category: Rhinovirus coat protein]]
 [[Category: Virus]]
 [[Category: Win compound]]