2jle: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
== | |||
==Novel indazole nnrtis created using molecular template hybridization based on crystallographic overlays== | |||
<StructureSection load='2jle' size='340' side='right' caption='[[2jle]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='2jle' size='340' side='right' caption='[[2jle]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jle]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JLE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JLE FirstGlance]. <br> | <table><tr><td colspan='2'>[[2jle]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JLE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JLE FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I15:5-[(5-FLUORO-3-METHYL-1H-INDAZOL-4-YL)OXY]BENZENE-1,3-DICARBONITRILE'>I15</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I15:5-[(5-FLUORO-3-METHYL-1H-INDAZOL-4-YL)OXY]BENZENE-1,3-DICARBONITRILE'>I15</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jle OCA], [http://pdbe.org/2jle PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jle RCSB], [http://www.ebi.ac.uk/pdbsum/2jle PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jle OCA], [http://pdbe.org/2jle PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jle RCSB], [http://www.ebi.ac.uk/pdbsum/2jle PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jle ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
| Line 10: | Line 11: | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jl/2jle_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jl/2jle_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 48: | Line 49: | ||
[[Category: Capsid maturation]] | [[Category: Capsid maturation]] | ||
[[Category: Capsid protein]] | [[Category: Capsid protein]] | ||
[[Category: Cytoplasm]] | |||
[[Category: Dna integration]] | [[Category: Dna integration]] | ||
[[Category: Dna recombination]] | [[Category: Dna recombination]] | ||
| Line 65: | Line 67: | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Ribosomal frameshifting]] | |||
[[Category: Rna-binding]] | [[Category: Rna-binding]] | ||
[[Category: Rna-directed dna polymerase]] | [[Category: Rna-directed dna polymerase]] | ||
| Line 70: | Line 73: | ||
[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
[[Category: Zinc]] | |||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 07:21, 11 July 2018
Novel indazole nnrtis created using molecular template hybridization based on crystallographic overlays
| ||||||||||||
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Allan, G
- Barba, O
- Burt, C
- Corbau, R
- Dupont, T
- Irving, S
- Jones, L H
- Mowbray, C E
- Phillips, C
- Swain, N A
- Webster, R
- Westby, M
- Aid
- Aspartyl protease
- Capsid maturation
- Capsid protein
- Cytoplasm
- Dna integration
- Dna recombination
- Dna-directed dna polymerase
- Endonuclease
- Hiv-1
- Hydrolase
- Lipoprotein
- Magnesium
- Metal-binding
- Multifunctional enzyme
- Myristate
- Nnrti
- Nuclease
- Nucleotidyltransferase
- Nucleus
- Phosphoprotein
- Protease
- Ribosomal frameshifting
- Rna-binding
- Rna-directed dna polymerase
- Transferase
- Viral nucleoprotein
- Virion
- Zinc
- Zinc-finger
