2w1i: Difference between revisions
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== | |||
==Structure determination of Aurora Kinase in complex with inhibitor== | |||
<StructureSection load='2w1i' size='340' side='right' caption='[[2w1i]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2w1i' size='340' side='right' caption='[[2w1i]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b7a|2b7a]], [[2w1g|2w1g]], [[2w1f|2w1f]], [[2w1d|2w1d]], [[2w1h|2w1h]], [[2w1e|2w1e]], [[2w1c|2w1c]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b7a|2b7a]], [[2w1g|2w1g]], [[2w1f|2w1f]], [[2w1d|2w1d]], [[2w1h|2w1h]], [[2w1e|2w1e]], [[2w1c|2w1c]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1i OCA], [http://pdbe.org/2w1i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w1i RCSB], [http://www.ebi.ac.uk/pdbsum/2w1i PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1i OCA], [http://pdbe.org/2w1i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w1i RCSB], [http://www.ebi.ac.uk/pdbsum/2w1i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w1i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w1/2w1i_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w1/2w1i_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Maman, S]] | [[Category: Maman, S]] | ||
[[Category: Matthews, J E]] | [[Category: Matthews, J E]] | ||
[[Category: | [[Category: McMenamin, R L]] | ||
[[Category: Navarro, E F]] | [[Category: Navarro, E F]] | ||
[[Category: Rees, D C]] | [[Category: Rees, D C]] | ||
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[[Category: Aurora]] | [[Category: Aurora]] | ||
[[Category: Cancer]] | [[Category: Cancer]] | ||
[[Category: Chromosomal rearrangement]] | |||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Polymorphism]] | |||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
[[Category: Sh2 domain]] | [[Category: Sh2 domain]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
