3cj4: Difference between revisions
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==Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments== | ==Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments== | ||
<StructureSection load='3cj4' size='340' side='right' caption='[[3cj4]], [[Resolution|resolution]] 2.07Å' scene=''> | <StructureSection load='3cj4' size='340' side='right' caption='[[3cj4]], [[Resolution|resolution]] 2.07Å' scene=''> | ||
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS5B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31647 Hepatitis C virus subtype 1b])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS5B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31647 Hepatitis C virus subtype 1b])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cj4 OCA], [http://pdbe.org/3cj4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cj4 RCSB], [http://www.ebi.ac.uk/pdbsum/3cj4 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cj4 OCA], [http://pdbe.org/3cj4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cj4 RCSB], [http://www.ebi.ac.uk/pdbsum/3cj4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cj4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cj4_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cj4_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Antonysamy, s s]] | [[Category: Antonysamy, s s]] | ||
[[Category: Acetylation]] | |||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Capsid protein]] | [[Category: Capsid protein]] | ||
[[Category: Cytoplasm]] | |||
[[Category: Drug discovery]] | [[Category: Drug discovery]] | ||
[[Category: Endoplasmic reticulum]] | [[Category: Endoplasmic reticulum]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Ubl conjugation]] | |||
[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
[[Category: Zinc]] | |||