1efy: Difference between revisions

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3,331,613 edits
No edit summary
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[[Image:1efy.jpg|left|200px]]
[[Image:1efy.jpg|left|200px]]


{{Structure
<!--
|PDB= 1efy |SIZE=350|CAPTION= <scene name='initialview01'>1efy</scene>, resolution 2.2&Aring;
The line below this paragraph, containing "STRUCTURE_1efy", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=BZC:2-(3&#39;-METHOXYPHENYL)+BENZIMIDAZOLE-4-CARBOXAMIDE'>BZC</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1efy| PDB=1efy  | SCENE= }}  
|RELATEDENTRY=[[2paw|2PAW]], [[1pax|1PAX]], [[2pax|2PAX]], [[3pax|3PAX]], [[4pax|4PAX]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1efy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1efy OCA], [http://www.ebi.ac.uk/pdbsum/1efy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1efy RCSB]</span>
}}


'''CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF POLY (ADP-RIBOSE) POLYMERASE COMPLEXED WITH A BENZIMIDAZOLE INHIBITOR'''
'''CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF POLY (ADP-RIBOSE) POLYMERASE COMPLEXED WITH A BENZIMIDAZOLE INHIBITOR'''
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Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase., White AW, Almassy R, Calvert AH, Curtin NJ, Griffin RJ, Hostomsky Z, Maegley K, Newell DR, Srinivasan S, Golding BT, J Med Chem. 2000 Nov 2;43(22):4084-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11063605 11063605]
Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase., White AW, Almassy R, Calvert AH, Curtin NJ, Griffin RJ, Hostomsky Z, Maegley K, Newell DR, Srinivasan S, Golding BT, J Med Chem. 2000 Nov 2;43(22):4084-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11063605 11063605]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: NAD(+) ADP-ribosyltransferase]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Almassy, R.]]
[[Category: Almassy, R.]]
Line 36: Line 32:
[[Category: Srinivasan, S.]]
[[Category: Srinivasan, S.]]
[[Category: White, A W.]]
[[Category: White, A W.]]
[[Category: benzimidazole]]
[[Category: Benzimidazole]]
[[Category: catalytic fragment]]
[[Category: Catalytic fragment]]
[[Category: crystal structure]]
[[Category: Crystal structure]]
[[Category: inhibitor]]
[[Category: Inhibitor]]
[[Category: polymerase]]
[[Category: Polymerase]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:01:45 2008''
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