2iu3: Difference between revisions

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==CRYSTAL STRUCTURES OF TRANSITION STATE ANALOGUE INHIBITORS OF INOSINE MONOPHOSPHATE CYCLOHYDROLASE==
 
==Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase==
<StructureSection load='2iu3' size='340' side='right' caption='[[2iu3]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='2iu3' size='340' side='right' caption='[[2iu3]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=203:1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE+2,2-DIOXIDE'>203</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=203:1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE+2,2-DIOXIDE'>203</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g8m|1g8m]], [[1m9n|1m9n]], [[1oz0|1oz0]], [[1thz|1thz]], [[2iu0|2iu0]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g8m|1g8m]], [[1m9n|1m9n]], [[1oz0|1oz0]], [[1thz|1thz]], [[2iu0|2iu0]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu3 OCA], [http://pdbe.org/2iu3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iu3 RCSB], [http://www.ebi.ac.uk/pdbsum/2iu3 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu3 OCA], [http://pdbe.org/2iu3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iu3 RCSB], [http://www.ebi.ac.uk/pdbsum/2iu3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iu3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/2iu3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/2iu3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>